• Investigación
• Cargo Conicet: Investigador Independiente
  Área: Biología Molecular y Celular
  Tema de Trabajo: Integración de señales ambientales mediante regulación redox en plantas.
  Descripción de trabajo: En nuestro laboratorio investigamos cómo las plantas ajustan su crecimiento y desarrollo en respuesta a cambios ambientales. Nos interesa comprender el papel de la regulación del estado redox celular como un mecanismo central en estos procesos adaptativos. En particular, estudiamos cómo las señales redox actúan como mensajeros celulares mediante modificaciones postraduccionales, principalmente sobre residuos de cisteína, que modulan la actividad de reguladores maestros y reconfiguran redes de señalización. Estas modificaciones constituyen mecanismos regulatorios dinámicos que permiten integrar de manera rápida y versátil las señales ambientales, contribuyendo a la adaptación y plasticidad del desarrollo vegetal.

Publicaciones seleccionadas
Tebez NM, Correa Aragunde N, Murcia G, Salvat S, Casco A, Fiol DF, Iglesias MJ§, Terrile MC§ (2026). Nitric Oxide Modulates Auxin Signaling through TIR1 S-Nitrosylation During Thermomorphogenesis in Arabidopsis. Plant Physiology and Biochemistry. Accepted.
Agrofoglio Y*, Iglesias MJ*, de Leone MJ, Hernando E, Lewinski M, Torres SB, Contino G, Yanovsky MJ, Staiger D, Mateos J (2026). In vivo binding by Arabidopsis SPLICING FACTOR 1 shifts 3′ splice site choice, regulating circadian rhythms and immunity in plants. Proceedings of the National Academy of Sciences, 123(23): e2531955123.
Iglesias MJ§, Costigliolo MC, Bianchimano L, Legris M, Blázquez MA, Zurbriggen MD, Casal JJ§ (2024). COP1 as a key redox-controlled regulator of hypocotyl growth under shade. Proceedings of the National Academy of Sciences, 121(42): e2320187121.
Agrofoglio Y*, Iglesias MJ*, Perez-Santangelo S, de Leone MJ, Köster T, Catalá R, Salinas J, Yanovsky MJ, Staiger D, Mateos J (2024). Antagonistic effects of arginine methylation of LSM4 on alternative splicing during plant stress responses. The Plant Cell. https://doi.org/10.1093/plcell/koae051.
Steffen A, Dombert K*, Iglesias MJ*, Nolte C, de Leone MJ, Yanovsky MJ, Staiger D (2024). Assessing the Role of AtGRP7 Arginine 141, a Target of Dimethylation by PRMT5, in Flowering Time Control and Stress Response. Plants, 13(19):2771.
Bianchimano L, De Luca B, Borniego B, Iglesias MJ§, Casal JJ§ (2023). Temperature regulation of auxin-related gene expression and its implications for plant growth. Journal of Experimental Botany, https://doi.org/10.1093/jxb/erad265.
Terrile MC, Tebez NM, Colman SL, Mateos JL, Estelle M, Martínez-Ruiz A, Fiol DF, Casalongué CA, Iglesias MJ§ (2022). S-nitrosation of SCF E3 ligase components regulates hormonal signaling in Arabidopsis. Frontiers in Plant Science, DOI: 10.3389/fpls.2021.794582.
Iglesias MJ, Colman SL, Terrile MC, Paris R, Martín-Saldaña S, Chevalier AA, Alvarez V, Casalongué CA (2019). Enhanced properties of chitosan microparticles over bulk chitosan on the modulation of auxin signaling pathway with beneficial impacts on root architecture in plants. Journal of Agricultural and Food Chemistry, 67:6911–6920.
Iglesias MJ, Sellaro R, Zurbriggen MD, Casal JJ (2018). Multiple links between shade avoidance and auxin networks. Journal of Experimental Botany, 69(2):213–228.
Iglesias MJ, Terrile MC, Correa-Aragunde MN, Fiol DF, Paris R, Lamattina L, Estelle M, Martínez-Ruiz A, Casalongué CA (2018). Regulation of SCF-TIR1/AFBs E3 ligase assembly by S-nitrosylation of Arabidopsis SKP1-like1 impacts on auxin signaling. Redox Biology, 18:200–210.
Pucciariello O, Iglesias MJ*, Legris M*, Costigliolo Rojas C*, Hernando E, Dezar C, Vázquez M, Yanovsky MJ, Finlayson SA, Prat S, Casal JJ (2018). Rewiring of auxin signaling under persistent shade. Proceedings of the National Academy of Sciences, 115(21):5612–5617.
Martín-Saldaña S, Iglesias MJ*, Chevalier MT*, Colman SP*, Casalongué CA, Alvarez V, Chevalier A (2018). Characterization of salicylic acid loaded chitosan microparticles with applications in horticultural plant species: A second life for shrimp fishing industry waste. Carbohydrate Polymers, 15:321–331.
Iglesias MJ, Terrile MC, Windels D, Lombardo C, Bartoli C, Vázquez F, Estelle M, Casalongué CA (2014). miR393 regulation of auxin signaling and redox-related components during acclimation to salinity in Arabidopsis. PLoS ONE, 9(9): e107678. doi:10.1371/journal.pone.0107678..
Paris R, Iglesias MJ, Terrile MC, Casalongué CA (2013). Functions of S-nitrosylation in plant hormone networks. Frontiers in Plant Science, 4:294, doi: 10.3389/fpls.2013.00294..
Terrile MC, Calderón Villalobos LIA, Paris R, Iglesias MJ, Lamattina L, Estelle M, Casalongué CA (2012). Nitric oxide regulates auxin signaling through S-nitrosylation of the Arabidopsis Transport Inhibitor Response1 auxin receptor. The Plant Journal, 70:492–500.
Iglesias MJ, Terrile MC, Bártoli C, D’Ippólito S, Casalongué CA (2010). Auxin signaling participates in the adaptive response against oxidative stress and salinity by interacting with redox metabolism in Arabidopsis. Plant Molecular Biology, 74:215–222.
*Co- autor. § Autor de correspondencia.