Cargo Conicet: Investigador Independiente
Área: Biotecnología
Tema de Trabajo: Genómica y Bioinformática de Patógenos
Descripción de trabajo: Obtenemos, analizamos e integramos datos x-ómicos de patógenos de interés en salud humana y animal mediante herramientas bioinformáticas y de biología molecular.

https://www.ncbi.nlm.nih.gov/myncbi/lau.ka.1/bibliography/public/

1: Maldonado LL, Arrabal JP, Rosenzvit MC, Oliveira GC, Kamenetzky L. Revisiting the Phylogenetic History of Helminths Through Genomics, the Case of the New Echinococcus oligarthrus Genome. Front Genet. 2019 Aug 7;10:708. doi:10.3389/fgene.2019.00708. eCollection 2019. PubMed PMID: 31440275; PubMed Central PMCID: PMC6692484.

2: Vaca HR, Celentano AM, Macchiaroli N, Kamenetzky L, Camicia F, Rosenzvit MC. Histone deacetylase enzymes as potential drug targets of Neglected Tropical Diseases caused by cestodes. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:120-132. doi: 10.1016/j.ijpddr.2019.02.003. Epub 2019 Feb 23. PubMed PMID:  30897528; PubMed Central PMCID: PMC6426703.

3: Basika T, Paludo GP, Araujo FM, Salim AC, Pais F, Maldonado L, Macchiaroli N,  Camargo de Lima J, Rosenzvit M, Oliveira GC, Kamenetzky L, Ferreira HB. Transcriptomic profile of two developmental stages of the cestode parasite Mesocestoides corti. Mol Biochem Parasitol. 2019 Apr;229:35-46. doi: 10.1016/j.molbiopara.2019.02.006. Epub 2019 Feb 21. PubMed PMID: 30797776.

4: Macchiaroli N, Cucher M, Kamenetzky L, Yones C, Bugnon L, Berriman M, Olson PD, Rosenzvit MC. Identification and expression profiling of microRNAs in Hymenolepis. Int J Parasitol. 2019 Mar;49(3-4):211-223. doi: 10.1016/j.ijpara.2018.07.005. Epub 2019 Jan 21. PubMed PMID: 30677390.

5: Maldonado LL, Stegmayer G, Milone DH, Oliveira G, Rosenzvit M, Kamenetzky L. Whole genome analysis of codon usage in Echinococcus. Mol Biochem Parasitol. 2018 Oct;225:54-66. doi: 10.1016/j.molbiopara.2018.08.001. Epub 2018 Aug 3. PubMed PMID: 30081061.

6: International Molecular Helminthology Annotation Network (IMHAN); IMHAN consortium authors include, Palevich N, Britton C, Kamenetzky L, Mitreva M, de Moraes Mourão M, Bennuru S, Quack T, Scholte LLS, Tyagi R, Slatko BE. Tackling Hypotheticals in Helminth Genomes. Trends Parasitol. 2018 Mar;34(3):179-183. doi: 10.1016/j.pt.2017.11.007. Epub 2017 Dec 14. PubMed PMID: 29249363.

7: Stegmayer G, Yones C, Kamenetzky L, Macchiaroli N, Milone DH. Computational Prediction of Novel miRNAs from Genome-Wide Data. Methods Mol Biol. 2017;1654:29-37. doi: 10.1007/978-1-4939-7231-9_3. PubMed PMID: 28986781.

8: Carnevale S, Malandrini JB, Pantano ML, Soria CC, Rodrigues-Silva R, Machado-Silva JR, Velásquez JN, Kamenetzky L. First genetic characterization of Fasciola hepatica in Argentina by nuclear and mitochondrial gene markers. Vet Parasitol. 2017 Oct 15;245:34-38. doi: 10.1016/j.vetpar.2017.08.006. Epub 2017 Aug 12. PubMed PMID: 28969834.

9: Pérez MG, Macchiaroli N, Lichtenstein G, Conti G, Asurmendi S, Milone DH, Stegmayer G, Kamenetzky L, Cucher M, Rosenzvit MC. microRNA analysis of Taenia crassiceps cysticerci under praziquantel treatment and genome-wide identification of Taenia solium miRNAs. Int J Parasitol. 2017 Sep;47(10-11):643-653. doi:10.1016/j.ijpara.2017.04.002. Epub 2017 May 17. PubMed PMID: 28526608.

10: Arrabal JP, Avila HG, Rivero MR, Camicia F, Salas MM, Costa SA, Nocera CG, Rosenzvit MC, Kamenetzky L. Echinococcus oligarthrus in the subtropical region of Argentina: First integration of morphological and molecular analyses determines two distinct populations. Vet Parasitol. 2017 Jun 15;240:60-67. doi: 10.1016/j.vetpar.2017.03.019. Epub 2017 Mar 27. PubMed PMID: 28433410.

11: Macchiaroli N, Maldonado LL, Zarowiecki M, Cucher M, Gismondi MI, Kamenetzky
L, Rosenzvit MC. Genome-wide identification of microRNA targets in the neglected
disease pathogens of the genus Echinococcus. Mol Biochem Parasitol. 2017
Jun;214:91-100. doi: 10.1016/j.molbiopara.2017.04.001. Epub 2017 Apr 3. PubMed
PMID: 28385564.

12: Maldonado LL, Assis J, Araújo FM, Salim AC, Macchiaroli N, Cucher M, Camicia
F, Fox A, Rosenzvit M, Oliveira G, Kamenetzky L. The Echinococcus canadensis (G7)
genome: a key knowledge of parasitic platyhelminth human diseases. BMC Genomics.
2017 Feb 27;18(1):204. doi: 10.1186/s12864-017-3574-0. PubMed PMID: 28241794;
PubMed Central PMCID: PMC5327563.

13: Avila HG, Santos GB, Cucher MA, Macchiaroli N, Pérez MG, Baldi G, Jensen O,
Pérez V, López R, Negro P, Scialfa E, Zaha A, Ferreira HB, Rosenzvit M,
Kamenetzky L. Implementation of new tools in molecular epidemiology studies of
Echinococcus granulosus sensu lato in South America. Parasitol Int. 2017
Jun;66(3):250-257. doi: 10.1016/j.parint.2017.02.001. Epub 2017 Feb 11. PubMed
PMID: 28193534.

14: Carnevale S, Malandrini JB, Pantano ML, Sawicki M, Soria CC, Kuo LH,
Kamenetzky L, Astudillo OG, Velásquez JN. Fasciola hepatica infection in humans:
overcoming problems for the diagnosis. Acta Parasitol. 2016 Dec 1;61(4):776-783.
doi: 10.1515/ap-2016-0107. PubMed PMID: 27787223.

15: Basika T, Macchiaroli N, Cucher M, Espínola S, Kamenetzky L, Zaha A,
Rosenzvit M, Ferreira HB. Identification and profiling of microRNAs in two
developmental stages of the model cestode parasite Mesocestoides corti. Mol
Biochem Parasitol. 2016 Nov – Dec;210(1-2):37-49. doi:
10.1016/j.molbiopara.2016.08.004. Epub 2016 Aug 17. PubMed PMID: 27544036.

16: Stegmayer G, Yones C, Kamenetzky L, Milone DH. High Class-Imbalance in
pre-miRNA Prediction: A Novel Approach Based on deepSOM. IEEE/ACM Trans Comput
Biol Bioinform. 2017 Nov-Dec;14(6):1316-1326. doi: 10.1109/TCBB.2016.2576459.
Epub 2016 Jun 7. PubMed PMID: 27295687.

17: Leskow CC, Kamenetzky L, Dominguez PG, Díaz Zirpolo JA, Obata T, Costa H,
Martí M, Taboga O, Keurentjes J, Sulpice R, Ishihara H, Stitt M, Fernie AR,
Carrari F. Allelic differences in a vacuolar invertase affect Arabidopsis growth
at early plant development. J Exp Bot. 2016 Jul;67(14):4091-103. doi:
10.1093/jxb/erw185. Epub 2016 May 18. PubMed PMID: 27194734.

18: Kamenetzky L, Stegmayer G, Maldonado L, Macchiaroli N, Yones C, Milone DH.
MicroRNA discovery in the human parasite Echinococcus multilocularis from
genome-wide data. Genomics. 2016 Jun;107(6):274-80. doi:
10.1016/j.ygeno.2016.04.002. Epub 2016 Apr 21. PubMed PMID: 27107656.

19: Cucher MA, Macchiaroli N, Baldi G, Camicia F, Prada L, Maldonado L, Avila HG,
Fox A, Gutiérrez A, Negro P, López R, Jensen O, Rosenzvit M, Kamenetzky L. Cystic
echinococcosis in South America: systematic review of species and genotypes of
Echinococcus granulosus sensu lato in humans and natural domestic hosts. Trop Med
Int Health. 2016 Feb;21(2):166-75. doi: 10.1111/tmi.12647. Epub 2015 Dec 28.
Review. PubMed PMID: 26610060.

20: Yones CA, Stegmayer G, Kamenetzky L, Milone DH. miRNAfe: A comprehensive tool
for feature extraction in microRNA prediction. Biosystems. 2015 Dec;138:1-5. doi:
10.1016/j.biosystems.2015.10.003. Epub 2015 Oct 20. PubMed PMID: 26499212.
21: Carnevale S, Pantano ML, Kamenetzky L, Malandrini JB, Soria CC, Velásquez JN.
Molecular diagnosis of natural fasciolosis by DNA detection in sheep faeces. Acta
Parasitol. 2015 Jun;60(2):211-7. doi: 10.1515/ap-2015-0030. PubMed PMID:
26203987.

22: Cucher M, Macchiaroli N, Kamenetzky L, Maldonado L, Brehm K, Rosenzvit MC.
High-throughput characterization of Echinococcus spp. metacestode miRNomes. Int J
Parasitol. 2015 Mar;45(4):253-67. doi: 10.1016/j.ijpara.2014.12.003. Epub 2015
Feb 4. PubMed PMID: 25659494.

23: Macchiaroli N, Cucher M, Zarowiecki M, Maldonado L, Kamenetzky L, Rosenzvit
MC. microRNA profiling in the zoonotic parasite Echinococcus canadensis using a
high-throughput approach. Parasit Vectors. 2015 Feb 6;8:83. doi:
10.1186/s13071-015-0686-8. PubMed PMID: 25656283; PubMed Central PMCID:
PMC4326209.

24: Milone DH, Stegmayer G, López M, Kamenetzky L, Carrari F. Improving
clustering with metabolic pathway data. BMC Bioinformatics. 2014 Apr 10;15:101.
doi: 10.1186/1471-2105-15-101. PubMed PMID: 24717120; PubMed Central PMCID:
PMC4002909.

25: Carnevale S, Cabrera MG, Cucher MA, di Risio CA, Malandrini JB, Kamenetzky L,
Alazraqui M, Etchart CB, Pantano ML, Velásquez JN. Direct, immunological and
molecular techniques for a fasciolosis survey in a rural area of San Luis,
Argentina. J Parasit Dis. 2013 Oct;37(2):251-9. doi: 10.1007/s12639-012-0175-3.
Epub 2012 Sep 28. PubMed PMID: 24431579; PubMed Central PMCID: PMC3793087.

26: Camicia F, Herz M, Prada LC, Kamenetzky L, Simonetta SH, Cucher MA, Bianchi
JI, Fernández C, Brehm K, Rosenzvit MC. The nervous and prenervous roles of
serotonin in Echinococcus spp. Int J Parasitol. 2013 Jul;43(8):647-59. doi:
10.1016/j.ijpara.2013.03.006. Epub 2013 Apr 29. PubMed PMID: 23639266.

27: Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, Sánchez-Flores A, Brooks
KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM,
Cai X, Camicia F, Clark R, Cucher M, De Silva N, Day TA, Deplazes P, Estrada K,
Fernández C, Holland PWH, Hou J, Hu S, Huckvale T, Hung SS, Kamenetzky L, Keane
JA, Kiss F, Koziol U, Lambert O, Liu K, Luo X, Luo Y, Macchiaroli N, Nichol S,
Paps J, Parkinson J, Pouchkina-Stantcheva N, Riddiford N, Rosenzvit M, Salinas G,
Wasmuth JD, Zamanian M, Zheng Y; Taenia solium Genome Consortium, Cai J, Soberón
X, Olson PD, Laclette JP, Brehm K, Berriman M. The genomes of four tapeworm
species reveal adaptations to parasitism. Nature. 2013 Apr 4;496(7443):57-63.
doi: 10.1038/nature12031. Epub 2013 Mar 13. PubMed PMID: 23485966; PubMed Central
PMCID: PMC3964345.

28: Cucher M, Mourglia-Ettlin G, Prada L, Costa H, Kamenetzky L, Poncini C,
Dematteis S, Rosenzvit MC. Echinococcus granulosus pig strain (G7 genotype)
protoscoleces did not develop secondary hydatid cysts in mice. Vet Parasitol.
2013 Mar 31;193(1-3):185-92. doi: 10.1016/j.vetpar.2012.11.027. Epub 2012 Nov 30.
PubMed PMID: 23265812.

29: Ferraro G, Bortolotti S, Mortera P, Schlereth A, Stitt M, Carrari F,
Kamenetzky L, Valle EM. Novel glutamate dehydrogenase genes show increased
transcript and protein abundances in mature tomato fruits. J Plant Physiol. 2012
Jun 15;169(9):899-907. doi: 10.1016/j.jplph.2012.02.002. Epub 2012 Mar 27. PubMed
PMID: 22459323.

30: Stegmayer G, Milone DH, Kamenetzky L, López MG, Carrari F. A biologically
inspired validity measure for comparison of clustering methods over metabolic
data sets. IEEE/ACM Trans Comput Biol Bioinform. 2012 May-Jun;9(3):706-16. doi:
10.1109/TCBB.2012.10. PubMed PMID: 22231623.

31: Milone DH, Stegmayer GS, Kamenetzky L, López M, Lee JM, Giovannoni JJ,
Carrari F. *omeSOM: a software for clustering and visualization of
transcriptional and metabolite data mined from interspecific crosses of crop
plants. BMC Bioinformatics. 2010 Aug 26;11:438. doi: 10.1186/1471-2105-11-438.
PubMed PMID: 20796314; PubMed Central PMCID: PMC2942854.

32: Kamenetzky L, Asís R, Bassi S, de Godoy F, Bermúdez L, Fernie AR, Van Sluys
MA, Vrebalov J, Giovannoni JJ, Rossi M, Carrari F. Genomic analysis of wild
tomato introgressions determining metabolism- and yield-associated traits. Plant
Physiol. 2010 Apr;152(4):1772-86. doi: 10.1104/pp.109.150532. Epub 2010 Jan 29.
PubMed PMID: 20118271; PubMed Central PMCID: PMC2850009.

33: Bermúdez L, Urias U, Milstein D, Kamenetzky L, Asis R, Fernie AR, Van Sluys
MA, Carrari F, Rossi M. A candidate gene survey of quantitative trait loci
affecting chemical composition in tomato fruit. J Exp Bot. 2008;59(10):2875-90.
doi: 10.1093/jxb/ern146. Epub 2008 Jun 13. PubMed PMID: 18552354; PubMed Central
PMCID: PMC2486480.

34: Camicia F, Paredes R, Chalar C, Galanti N, Kamenetzky L, Gutierrez A,
Rosenzvit MC. Sequencing, bioinformatic characterization and expression pattern
of a putative amino acid transporter from the parasitic cestode Echinococcus
granulosus. Gene. 2008 Mar 31;411(1-2):1-9. doi: 10.1016/j.gene.2007.11.023. Epub
2008 Feb 12. PubMed PMID: 18272295.

35: Muzulin PM, Kamenetzky L, Gutierrez AM, Guarnera EA, Rosenzvit MC.
Echinococcus granulosus antigen B gene family: further studies of strain
polymorphism at the genomic and transcriptional levels. Exp Parasitol. 2008
Feb;118(2):156-64. Epub 2007 Aug 3. PubMed PMID: 17825293.

36: Roratto PA, Bartholomei-Santos ML, Gutierrez AM, Kamenetzky L, Rosenzvit MC,
Zaha A. Detection of genetic polymorphism among and within Echinococcus
granulosus strains by heteroduplex analysis of a microsatellite from the U1 snRNA
genes. Genet Mol Res. 2006 Sep 30;5(3):542-52. PubMed PMID: 17117370.

37: Rosenzvit MC, Camicia F, Kamenetzky L, Muzulin PM, Gutierrez AM.
Identification and intra-specific variability analysis of secreted and
membrane-bound proteins from Echinococcus granulosus. Parasitol Int. 2006;55
Suppl:S63-7. Epub 2005 Dec 20. Review. PubMed PMID: 16368261.

38: Kamenetzky L, Muzulin PM, Gutierrez AM, Angel SO, Zaha A, Guarnera EA,
Rosenzvit MC. High polymorphism in genes encoding antigen B from human infecting
strains of Echinococcus granulosus. Parasitology. 2005 Dec;131(Pt 6):805-15.
PubMed PMID: 16336734.

39: Lorenzo C, Ferreira HB, Monteiro KM, Rosenzvit M, Kamenetzky L, García HH,
Vasquez Y, Naquira C, Sánchez E, Lorca M, Contreras M, Last JA, González-Sapienza
GG. Comparative analysis of the diagnostic performance of six major Echinococcus
granulosus antigens assessed in a double-blind, randomized multicenter study. J
Clin Microbiol. 2005 Jun;43(6):2764-70. PubMed PMID: 15956395; PubMed Central
PMCID: PMC1151937.

40: Guarnera EA, Parra A, Kamenetzky L, García G, Gutiérrez A. Cystic
echinococcosis in Argentina: evolution of metacestode and clinical expression in
various Echinococcus granulosus strains. Acta Trop. 2004 Oct;92(2):153-9. PubMed
PMID: 15350868.

41: Haag KL, Ayala FJ, Kamenetzky L, Gutierrez AM, Rosenzvit M. Livestock trade
history, geography, and parasite strains: the mitochondrial genetic structure of
Echinococcus granulosus in Argentina. J Parasitol. 2004 Apr;90(2):234-9. PubMed
PMID: 15165043.

42: Bartholomei-Santos ML, Heinzelmann LS, Oliveira RP, Chemale G, Gutierrez AM,
Kamenetzky L, Haag KL, Zaha A. Isolation and characterization of microsatellites
from the tapeworm Echinococcus granulosus. Parasitology. 2003 Jun;126(Pt
6):599-605. PubMed PMID: 12866799.

43: Kamenetzky L, Gutierrez AM, Canova SG, Haag KL, Guarnera EA, Parra A, García
GE, Rosenzvit MC. Several strains of Echinococcus granulosus infect livestock and
humans in Argentina. Infect Genet Evol. 2002 Dec;2(2):129-36. PubMed PMID:
12797989.

44: Rosenzvit MC, Canova SG, Kamenetzky L, Guarnera EA. Echinococcus granulosus:
intraspecific genetic variation assessed by a DNA repetitive element.
Parasitology. 2001 Oct;123(Pt 4):381-8. PubMed PMID: 11676370.

45: Kamenetzky L, Canova SG, Guarnera EA, Rosenzvit MC. Echinococcus granulosus:
DNA extraction from germinal layers allows strain determination in fertile and
nonfertile hydatid cysts. Exp Parasitol. 2000 Jun;95(2):122-7. Erratum in: Exp
Parasitol 2000 Dec;96(4):260. PubMed PMID: 10910713.

46: Rosenzvit MC, Zhang LH, Kamenetzky L, Canova SG, Guarnera EA, McManus DP.
Genetic variation and epidemiology of Echinococcus granulosus in Argentina.
Parasitology. 1999 May;118 ( Pt 5):523-30. PubMed PMID: 10363285.

47: Rosenzvit MC, Canova SG, Kamenetzky L, Ledesma BA, Guarnera EA. Echinococcus
granulosus: cloning and characterization of a tandemly repeated DNA element. Exp
Parasitol. 1997 Sep;87(1):65-8. PubMed PMID: 9287959.